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282 Articles Related To: previous page < results 1 - 100 >
Synthesis of chiral 1,2-diols and related compounds of biological activities via stepwise ring fission of 5-alkyl-6,8-dioxabicyclo[3.2.1]octane skeleton
Tetrahedron Letters, Volume 27, Issue 2, 1986, Pages 231-234
Yukio Masaki, Yuzuru Serizawa, Kinnosuke Nagata, Hirohisa Oda, Hiromu Nagashima, Kenji Kaji
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1. You are entitled to access the full text of this document
The synthesis and characterization of N-(diphenylthiophosphinyl)-P-phenyl-thiophosphonamidic acid phenyl ester and related compounds chiral at phosphorus
Inorganic Chemistry Communications, Volume 4, Issue 1, January 2001, Pages 36-40
Marek Necas, Mark R. St J. Foreman, Dalibor Dastych, Josef Novosad
2. You are entitled to access the full text of this document
Absolute configurations of 24-hydroxycholesterol and related compounds
Tetrahedron Letters, Volume 16, Issue 26, 1975, Pages 2203-2206
Naoyuki Koizumi, Masuo Morisaki, Nobuo Ikekawa, Atsuo Suzuki and, Toru Takeshita
3. You are entitled to access the full text of this document
Synthesis and electrospray mass spectrometric studies on a chiral, non-racemic, phosphoramide receptor molecule
Tetrahedron: Asymmetry, Volume 10, Issue 17, 27 August 1999, Pages 3267-3271
Athene R. C. Smith, Albert J. R. Heck, Jennifer A. Kenny, J. Jantien Kettenes-van den Bosch, Martin Wills
4. You are entitled to access the full text of this document
Chiral Genetics of Drugs and Related Compounds
Advances in BioChirality, 1999, Pages 347-360
Béla Noszál
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Subject index
Studies in Natural Products Chemistry, Volume 24, Part 5, 2000, Pages 1139-1156
6. You are entitled to access the full text of this document
Synthesis and biological activities of degraded limonoids, (±)-fraxinellonone and its related compounds
Tetrahedron Letters, Volume 38, Issue 2, 13 January 1997, Pages 263-266
Hiroaki Okamura, Keiko Yamauchi, Keiji Miyawaki, Tetsuo Iwagawa, Munehiro Nakatani

Graphical Abstract

The first synthesis of (±)-fraxinellonone (1a) and its short step conversion into (±)-fraxinellone (2a) and (±)-isofraxinellone (3a) is described. The synthesized compounds exhibited moderate insect-antifeeding activity and ichthyotoxicity.
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Synthesis of Some Newo-Substituted Arylcarbamates and Related Compounds
Bioorganic Chemistry, Volume 25, Issue 1, February 1997, Pages 37-41
José E. Barbarini, Roberto Rittner, Nelci F. Höehr, Jerzy Suwinski
8. You are entitled to access the full text of this document
Chapter 5.3: Five-membered ring systems: furans and benzofurans
Progress in Heterocyclic Chemistry, Volume 20, 2009, Pages 152-189
Xue-Long Hou, Zhen Yang, Kap-Sun Yeung, Henry N.C. Wong
9. You are entitled to access the full text of this document
1,4-Addition of chiral 2-propenylphosphonamide anions to α-substituted cyclopentenones: use in enantioselective syntheses of methyl dihydrojasmonates and methyl jasmonates
Tetrahedron Letters, Volume 42, Issue 41, 8 October 2001, Pages 7325-7328
Helen C Hailes, Ben Isaac, M.Hashim Javaid
The addition of chiral 2-propenylphosphonamide anions to α-substituted cyclopentenones afforded adducts in good yields and selectivities, which were subsequently ozonolysed leading to the synthesis of both enantiomers of methyl dihydrojasmonate and methyl jasmonate.
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Asymmetric cyclopropanation of chiral (1-dimethoxyphosphoryl-2-phenyl)vinyl p-tolyl sulfoxide: a new synthesis of enantiomerically pure 2-amino-3-phenyl-1-cyclopropane-phosphonic acid—a constrained analog of phaclofen
Tetrahedron Letters, Volume 43, Issue 16, 15 April 2002, Pages 3061-3065
Wanda H Midura, Marian Mikołajczyk
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11. You are entitled to access the full text of this document
Seco-oestradiols and some non-steroidal oestrogens: Structural correlates of oestrogenic action
Journal of Steroid Biochemistry, Volume 11, Issue 1, Part 1, July 1979, Pages 67-77
S. Durani, A. K. Agarwal, R. Saxena, B. S. Setty, R. C. Gupta, P. L. Kole, S. Ray, Nitya Anand
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Keyword index
European Journal of Medicinal Chemistry, Volume 26, Issue 9, December 1991, Pages 971-982
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The syntheses and biological activities of o-aminophenylalanine and related compounds
Archives of Biochemistry and Biophysics, Volume 102, Issue 1, July 1963, Pages 48-51
Alvie L. Davis, Rodney Lloyd, John Fletcher, Lynn Bayliss, Tommy J. McCord
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The structure of dicoumarol and related compounds
Tetrahedron, Volume 25, Issue 12, 1969, Pages 2531-2537
D. W. Hutchinson, J. A. Tomlinson
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The Literature of Heterocyclic Chemistry, Part IX, 2002–2004
Advances in Heterocyclic Chemistry, Volume 92, 2006, Pages 145-258
L.I. Belen’kii, V.N. Gramenitskaya, Yu.B. Evdokimenkova
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Subject index 1983
Tetrahedron Letters, Volume 24, Issue 1, 1983, Pages i-xlviii
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Keyword index
European Journal of Medicinal Chemistry, Volume 28, Issue 12, 1993, Pages 988-996
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Subject index
European Journal of Medicinal Chemistry, Volume 23, Issue 6, November-December 1988, Pages 603-610
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Keywords index
European Journal of Medicinal Chemistry, Volume 41, Issue 12, December 2006, Pages 1507-1521
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Biological activity of melatonin and some analogous: geometrical and electrical requirements
Journal of Molecular Structure: THEOCHEM, Volume 537, Issues 1-3, 12 March 2001, Pages 271-281
J. A. López Sastre, R. N. Miguel, R. P. Molina, M. C. G. Zarzuelo, C. Romero-Ávila, A. G. Ramos
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The chemistry of enediynes, enyne allenes and related compounds
Tetrahedron, Volume 52, Issue 19, 6 May 1996, Pages 6453-6518
Janet Wisniewski Grissom, Gamini U. Gunawardena, Detlef Klingberg, Dahai Huang
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Intramolecular hydrogen abstraction reaction in carbohydrate chemistry. Synthesis of chiral 2,7-dioxabicyclo[2.2.1]heptane and 6,8-dioxabicyclo[3.2.1]octane ring systems
Tetrahedron Letters, Volume 41, Issue 41, 7 October 2000, Pages 7869-7873
Cosme G. Francisco*, Antonio J. Herrera, Ernesto Suárez
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Design, synthesis and antiproliferative activity of methyl 4-Iodo-1-β-D-ribofuranosyl-pyrazole-3-carboxylate and related compounds
Bioorganic & Medicinal Chemistry Letters, Volume 6, Issue 11, 4 June 1996, Pages 1279-1284
Stefano Manfredini, Rita Bazzanini, Pier Giovanni Baraldi, Daniele Simoni, Silvia Vertuani, Alessandra Pani, Elisabetta Pinna, Franca Scintu, Donatella Lichino, Paolo La Colla

Graphical Abstract

Azole-nucleoside analogs characterised, for the first time, by a carboxylic ester or an oxadiazole moieties are described. In contrast to the known SAR in this class of nucleosides a methyl ester was more active than the corresponding primary amide.
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Design, synthesis and biological activity of some 4-DAMP- related compounds
Bioorganic & Medicinal Chemistry Letters, Volume 5, Issue 20, 19 October 1995, Pages 2325-2330
Vincenzo Tumiatti, Santi Spampinato, Maurizio Recanatini, Anna Minarini, Carlo Melchiorre*, Alberto Chiarini, Roberta Budriesi

Graphical Abstract

The synthesis and muscarinic blocking activity of two constrained analogues of 4-DAMP are detailed. It turned out that these analogues are highly selective for muscarinic M1 receptors.
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Synthesis of 25-fluoroponasterone A, a fluorinated analogue of 20-hdyroxyecdysone.
Tetrahedron, Volume 48, Issue 44, 1992, Pages 9809-9818
Jaime Tomás, Francisco Camps, José Coll, Enric Melé, Nuria Pascual

Graphical Abstract

Very precise reaction conditions were required to accomplish the selective synthesis of the title compound from 20-hydroxyecdysone through the corresponding diacetonide.
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The Literature of Heterocyclic Chemistry, Part VIII, 1999–2001
Advances in Heterocyclic Chemistry, Volume 87, 2004, Pages 1-83
L. I. BELEN’KII, V. N. GRAMENITSKAYA
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Facile transformation of 3,4-disubstituted 2-azetidinones to chiral 5,6-dihydro-2-pyridones
Tetrahedron Letters, Volume 42, Issue 20, 14 May 2001, Pages 3483-3486
Hyeon Kyu Lee, Jong Soo Chun, Chwang Siek Pak
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Synthesis of 6-O-phosphorylated analogue of the antithrombin III binding sequence of heparin: replacement of one essential sulphate group by a phosphate group nullifies the biological activity.
Bioorganic & Medicinal Chemistry Letters, Volume 1, Issue 3, 1991, Pages 143-146
Jan. N. Vos, Pieter Westerdiun, Constant A. A. van Boeckel

Graphical Abstract


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Subject Index
Studies in Natural Products Chemistry, Volume 23, 2000, Pages 867-909
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Synthesis and plant growth inhibitory activities of (+)- and (−)-(2Z,4E)-5-(1′,2′-epoxy-2′,6′,6′-trimethylcyclohexyl)-3-methyl-2,4-pentadienoic acid
Phytochemistry, Volume 22, Issue 9, 1983, Pages 1909-1912
Takayuki Oritani, Kyohei Yamashita
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A new synthetic method for allene-1,3-dicarboxylates using DMC and a novel tandem cyclization to a pyrrolizidine alkaloid skeleton
Tetrahedron Letters, Volume 39, Issue 35, 27 August 1998, Pages 6331-6334
Manabu Node, Toshio Fujiwara, Shogo Ichihashi, Kiyoharu Nishide
Graphic
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The alkaline and acidic degradation of 3-amino-1,2,3-benzotriazin-4-one and related compounds
Tetrahedron, Volume 21, Issue 9, 1965, Pages 2191-2195
M. S. Gibson, M. Green
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An ynolate-initiated tandem process giving cyclopentenones: total synthesis of cucumin E
Tetrahedron Letters, Volume 43, Issue 29, 15 July 2002, Pages 5039-5041
Mitsuru Shindo, Yusuke Sato, Kozo Shishido
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Subject index
European Journal of Medicinal Chemistry, Volume 25, Issue 9, November-December 1990, Pages 799-808
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Graphical abstracts
Bioorganic & Medicinal Chemistry, Volume 1, Issue 3, September 1993, Pages iii-vi
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Cytokinins: Synthesis and biological activity of zeatin esters and related compounds
Phytochemistry, Volume 10, Issue 2, February 1971, Pages 275-280
Ruth Y. Schmitz, Folke Skoog, Sidney M. Hecht and, Nelson J. Leonard
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First synthesis of 5-fluoro-(+)-MK7607, its 1-epimer and 6-deoxy derivative
Tetrahedron Letters, Volume 49, Issue 38, 15 September 2008, Pages 5548-5550
João Sardinha, Amelia Pilar Rauter, Matthieu Sollogoub

Graphical abstract


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Synthesis of fluorinated analogs of natural porphyrins potentially useful for the diagnosis and therapy of cancer
Journal of Fluorine Chemistry, Volume 109, Issue 1, June 2001, Pages 67-81
Itsumaro Kumadaki, Akira Ando, Masaaki Omote
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Keyword index
European Journal of Medicinal Chemistry, Volume 24, Issue 6, November-December 1989, Pages 653-661
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The first synthesis of enantiomerically pure cyclopropylphosphonate analogues of nucleotides via asymmetric cyclopropanation of chiral (1-diethoxyphosphoryl)vinyl p-tolyl sulfoxide
Tetrahedron: Asymmetry, Volume 14, Issue 10, 16 May 2003, Pages 1245-1249
Wanda H. Midura, Jerzy A. Krysiak, Marian Mikolajczyk

Graphical Abstract


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Stereochemistry Abstracts


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(SS,1S,2S)-(1-Diethoxyphosphoryl-2-ethoxycarbonyl)cyclopropyl p-tolyl sulfoxide

C17H26O6PSEe=100%[α]D20=+39.0 (c 0.2, Me2CO)Source of chirality: asymmetric synthesisAbsolute configuration: (SS,1S,2S)

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(SS,1R,2R)-(1-Diethoxyphosphoryl-2-ethoxycarbonyl)cyclopropyl p-tolyl sulfoxide

C17H26O6PSEe=100%[α]D20=+137.0 (c 0.3, Me2CO)Source of chirality: asymmetric synthesisAbsolute configuration: (SS,1R,2R)

image

(SS,1S,2R)-(1-Diethoxyphosphoryl-2-ethoxycarbonyl)cyclopropyl p-tolyl sulfoxide

C17H26O6PSEe=100%[α]D20=+94.0 (c 0.21, Me2CO)Source of chirality: asymmetric synthesisAbsolute configuration: (SS,1S,2R)

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(1R,2S)-1-Diethoxyphosphoryl-2-ethoxycarbonylcyclopropane

C10H20O5PEe=100%[α]D20=−26.0 (c 0.23, Me2CO)Source of chirality: asymmetric synthesisAbsolute configuration: (1R,2S)

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(1R,2S)-1-Diethoxyphosphoryl-2-hydroxymethylcyclopropane

C8H17O4PEe=100%[α]D20=−24.0 (c 0.19, Me2CO)Source of chirality: asymmetric synthesisAbsolute configuration: (1R,2S)

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(1R,2S)-1-Diethoxyphosphoryl-2-[adenin-9-yl]methylcyclopropane

C13H21N5O3PEe=100%[α]D20=−8.2 (c 0.3, Me2CO)Source of chirality: asymmetric synthesisAbsolute configuration: (1R,2S)

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(1R,2S)-1-Diethoxyphosphoryl-2-[6-chloropurin-9-yl]methylcyclopropane

C13H19ClN4O3PEe=100%[α]D20=−2.2 (c 0.23, Me2CO)Source of chirality: asymmetric synthesisAbsolute configuration: (1R,2S)

41. You are entitled to access the full text of this document
Isocytosine H2-receptor histamine antagonists. IV. The synthesis and biological activity of donetidine (SK&F 93574) and related compounds
European Journal of Medicinal Chemistry, Volume 28, Issues 7-8, 1993, Pages 601-608
TH Brown, RC Blakemore, GJ Durant, CR Ganellin, ME Parsons, AC Rasmussen, DA Rawlings
42. You are entitled to access the full text of this document
The juvenile hormone - iv. Stereochemistry of juvenile hormone and biological activity of some of its isomers and related compounds
Life Sciences, Volume 7, Issue 4, 15 February 1968, Pages 129-137
Karl Heinz Dahm, Herbert Röller, Barry M. Trost
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Isoquinuclidine-based expectorants. Synthesis and biological activities of N-alkoxybenzylisoquinuclidines
European Journal of Medicinal Chemistry, Volume 32, Issue 5, May 1997, Pages 377-384
M Yokota, E Takizawa, Y Ohkura, C Fukai, T Tomiyama
44. You are entitled to access the full text of this document
Novel synthesis and γ-alkylation reactions of 4-(1-pyrrolidinyl)-2(5H)-thiophenones
Tetrahedron Letters, Volume 42, Issue 45, 5 November 2001, Pages 8011-8013
Yu-Jang Li, Zen-Ting Liu, Sheng-Chuan Yang
Graphic
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Synthesis and antitumoral activities of marine ent-chromazonarol and related compounds
Bioorganic & Medicinal Chemistry Letters, Volume 9, Issue 16, 16 August 1999, Pages 2325-2328
Alejandro F. Barrero, Enrique J. Alvarez-Manzaneda, M. Mar Herrador, Rachid Chahboun, P. Galera

Graphical Abstract

Efficient syntheses of ent-isozonarol (6a), ent-isozonarone (7a) and the marine ent-chromazonarol (8) from (−)-sclareol (12) are described. 6a and 7 show a significative antitumoral activty.
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Covalent analogues of DNA base-Pairs and triplets. Part 2: Synthesis and cytostatic activity of bis(purin-6-yl)acetylenes,-diacetylenes and related compounds
Bioorganic & Medicinal Chemistry Letters, Volume 12, Issue 7, 8 April 2002, Pages 1055-1058
Michal Hocek, Ivan Votruba

Graphical Abstract


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Cumulative Index for Volumes 37–57
Advances in Organometallic Chemistry, Volume 57, 2008, Pages 465-470
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Synthesis and structure of chiral N,N’-diaryl-α-naphthamidinium-N-[1,2,3,4-tetra-(methoxycarbonyl)cyclopentadien-5-yl] ylides and their metal complexes
Mendeleev Communications, Volume 7, Issue 4, 1997, Pages 127-129
Galina A. Dushenko, Igor E. Mikhailov, Olga E. Kompan, Adolf Zschunke, Gunter Reck, Burkhard Schulz, Clemens Mugge, Vladimir I. Minkin
49. You are entitled to access the full text of this document
Synthesis and biological activity of β-fluoroalkyl β-amino alcohols
Journal of Fluorine Chemistry, Volume 97, Issues 1-2, 20 July 1999, Pages 27-49
Pierfrancesco Bravo, Marcello Crucianelli, Taizo Ono, Matteo Zanda
50. You are entitled to access the full text of this document
Synthesis and biological activity of both (E)- and (Z)-isomers of optically pure (S)-14-methyl-8-hexadecenal (trogodermal), the antipodes of the pheromone of the khapra beetle
Tetrahedron, Volume 38, Issue 15, 1982, Pages 2291-2297
K. Mori, S. Kuwahara, H. Z. Levinson and, A. R. Levinson
51. You are entitled to access the full text of this document
Synthesis of methyl 3-amino-2-hydroxy-4-phenylbutanoates, important core intermediates for peptide mimics possessing biological activities
Tetrahedron Letters, Volume 42, Issue 11, 11 March 2001, Pages 2145-2147
Hisao Nemoto, Rujian Ma, Xinming Li, Ichiro Suzuki, Masayuki Shibuya
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γ-Pyrone natural products—A privileged compound class provided by nature
Bioorganic & Medicinal Chemistry, Volume 17, Issue 6, 15 March 2009, Pages 2304-2309
Wolfram Wilk, Herbert Waldmann, Markus Kaiser

Graphical abstract


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Studies on novel and chiral 1,4-dihydropyridines. V. Hantzsch-type 1,4-dihydropyridines having a chiral sulfinyl group: Syntheses, structures, and biological activity as a calcium channel antagonist,
Tetrahedron, Volume 53, Issue 12, 24 March 1997, Pages 4279-4290
Kazuyuki Miyashita, Masahiro Nishimoto, Tetsuya Ishino, Hidenobu Murafuji, Satoshi Obika, Osamu Muraoka, Takeshi Imanishi

Graphical Abstract

4-Aryl and 4-methyl substituted Hantzsch-type 1,4-dihydropyridines having a chiral sulfinyl group at C-5 were synthesized. The relation between calcium channel antagonist activity and the structures of 4-aryl derivatives was also discussed.
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Synthesis and synthetic applications of 2-amino-3-halo-1-oxypropanes
Tetrahedron, Volume 64, Issue 15, 7 April 2008, Pages 3275-3285
Matthias D'hooghe, Norbert De Kimpe

Graphical abstract


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Chapter 5.7 Five-membered ring systems with O & N atoms
Progress in Heterocyclic Chemistry, Volume 12, 2000, Pages 219-236
Thomas L. Gilchrist
56. You are entitled to access the full text of this document
Graphical abstracts
Tetrahedron Letters, Volume 32, Issue 46, 11 November 1991, Pages 6657-6666
57. You are not entitled to access the full text of this document
Chapter 1 Introduction: Nature, occurrence and functioning of plant hormones
New Comprehensive Biochemistry, Volume 33, 1999, Pages 3-22
RobertE. Cleland
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Biological activities and mechanisms of action of PGJ2 and related compounds: an update
Prostaglandins, Leukotrienes and Essential Fatty Acids, Volume 47, Issue 1, September 1992, Pages 1-12
M. Fukushima
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Synthesis of the acyl side chain segment of polyoxypeptins using regioselective ring-opening of chiral 2,3-epoxy alcohol
Tetrahedron Letters, Volume 43, Issue 51, 16 December 2002, Pages 9391-9395
Kazuishi Makino, Tatsuya Suzuki, Shinobu Awane, Osamu Hara, Yasumasa Hamada
Graphic
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Platelet activating factor; chemical and biochemical characteristics
Progress in Lipid Research, Volume 26, Issue 1, 1987, Pages 1-28
Donald J. Hanahan, Raj Kumar
61. You are entitled to access the full text of this document
Synthesis and anti-acetylcholinesterase activity of 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine hydrochloride (E2020) and related compounds
Bioorganic & Medicinal Chemistry Letters, Volume 2, Issue 8, August 1992, Pages 871-876
Hachiro Sugimoto, Youichi Iimura, Yoshiharu Yamanishi, Kiyomi Yamatsu

Graphical Abstract

The structure-activity relationship of E2020 and related compounds as acetylcholinesterase inhibitors is described.
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Extension of ring switching strategy to the glutamate antagonist 2-(pyrimidin-2,4-dione-5-ylmethyl)-(2S)-glycine and related compounds with two chiral centres
Tetrahedron Letters, Volume 41, Issue 51, 16 December 2000, Pages 10153-10158
Andrew Dinsmore, Paul M. Doyle, Peter B. Hitchcock, Douglas W. Young
63. You are not entitled to access the full text of this document
6 The Literature of Medicinal Chemistry
Progress in Medicinal Chemistry, Volume 6, 1969, Pages 266-360
G.P. Ellis
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Synthesis of a cyanopeptide-analogue with trypsin activating properties
Bioorganic & Medicinal Chemistry Letters, Volume 10, Issue 8, April 2000, Pages 779-781
Gregor Radau, Daniel Rauh
65. You are entitled to access the full text of this document
First total synthesis of (±)-AM6898A by stereoselective aldol cyclization
Tetrahedron Letters, Volume 41, Issue 44, 28 October 2000, Pages 8505-8508
Yoshio Fukuda, Masahiro Sakurai, Yasushi Okamoto
66. You are entitled to access the full text of this document
Rapid access to enantiopure bupropion and its major metabolite by stereospecific nucleophilic substitution on an α-ketotriflate
Tetrahedron: Asymmetry, Volume 11, Issue 18, 22 September 2000, Pages 3659-3663
Qun K. Fang, Zhengxu Han, Paul Grover, Donald Kessler, Chris H. Senanayake*, Stephen A. Wald
67. You are entitled to access the full text of this document
Isocytosine H2-receptor histamine antagonists. III. The synthesis and biological activity of lupitidine (SK&F 93479) and related compounds
European Journal of Medicinal Chemistry, Volume 25, Issue 3, April 1990, Pages 217-226
TH Brown, MA Armitage, RC Blakemore, P Blurton, GJ Durant, CR Ganellin, RJ Ife, ME Parsons, DA Rawlings, BP Slingsby
68. You are entitled to access the full text of this document
A simple and efficient approach to the synthesis of 4H-furo[3,4-b]pyrans via a three-component reaction of isocyanides
Bioorganic & Medicinal Chemistry Letters, Volume 18, Issue 14, 15 July 2008, Pages 3968-3970
Ahmad Shaabani, Ebrahim Soleimani, Afshin Sarvary, Ali Hossein Rezayan

Graphical abstract


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69. You are not entitled to access the full text of this document
3 Some Pyrimidines of Biological and Medicinal Interest—I
Progress in Medicinal Chemistry, Volume 6, 1969, Pages 67-134
G.C. Cheng
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Raney nickel desulfurization of 19-norsteroid ethylenethioketals : Synthesis of 4-estrene-2, 17-dione and related compounds
Tetrahedron, Volume 18, Issue 11, 1962, Pages 1251-1256
P. Narasimha Rao, H. R. Gollberg
71. You are entitled to access the full text of this document
Structure–activity relationships of trans-3,5-disubstituted pyrrolidinylthio-1β-methylcarbapenems. Part 2: J-111,225, J-114,870, J-114,871 and related compounds
Bioorganic & Medicinal Chemistry Letters, Volume 10, Issue 2, 17 January 2000, Pages 115-118
Hideaki Imamura, Norikazu Ohtake, Aya Shimizu, Hiroki Sato, Yuichi Sugimoto, Shunji Sakuraba, Hideo Kiyonaga, Chihiro Suzuki-Sato, Masato Nakano, Rie Nagano, Koji Yamada, Terutaka Hashizume, Hajime Morishima
72. You are entitled to access the full text of this document
Novel cephalosporin derivatives possessing a bicyclic heterocycle at the 3-Position. Part I: synthesis and biological activities of 3-(Benzothiazol-2-yl)thiocephalosporin derivatives, CP0467 and related compounds
Bioorganic & Medicinal Chemistry, Volume 6, Issue 7, July 1998, Pages 1009-1017
Masaki Tsushima, Katsuyoshi Iwamatsu, Atsushi Tamura, Seiji Shibahara
73. You are entitled to access the full text of this document
Short and stereoselective synthesis of manzacidins A and C, and their enantiomers
Tetrahedron Letters, Volume 49, Issue 52, 22 December 2008, Pages 7426-7429
Kentaro Oe, Tetsuro Shinada, Yasufumi Ohfune

Graphical abstract


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Synthesis of amide compounds of ferulic acid, and their stimulatory effects on insulin secretion in vitro
Bioorganic & Medicinal Chemistry, Volume 11, Issue 17, 15 August 2003, Pages 3807-3813
Eisaku Nomura, Ayumi Kashiwada, Asao Hosoda, Kozo Nakamura, Hideko Morishita, Takuo Tsuno, Hisaji Taniguchi

Graphical Abstract

The amides from ferulic acid were synthesized. Investigations of stimulatory effects of the amides on insulin secretion using rat pancreatic RIN-5F cells are described.
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The absolute configuration of prunioside A from Spiraea prunifolia and biological activities of related compounds
Phytochemistry, Volume 64, Issue 6, November 2003, Pages 1113-1118
Hyuncheol Oh, Hyungsoo Shin, Gi-Su Oh, Hyun-Ock Pae, Kyu-Yun Chai, Hun-Taeg Chung, Ho-Sub Lee

Graphical Abstract

The stereochemistry of prunioside A was determined by chemical transformations and NMR data analysis. Compounds related to prunioside A have inhibitory effects on the synthesis of nitric oxide in LPS-stimulated macrophage-like RAW 264.7 cells.
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Allenic and cumulenic lipids
Progress in Lipid Research, Volume 46, Issue 6, November 2007, Pages 328-375
Valery M. Dembitsky, Takashi Maoka
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A convenient synthesis of 2-amino-2-oxazolines and their pharmacological evaluation at cloned human α adrenergic receptors
Bioorganic & Medicinal Chemistry Letters, Volume 4, Issue 19, 6 October 1994, Pages 2317-2322
Wai C. Wong, Diana Wang, Carlos Forray, Pierre J. -J. Vaysse, Theresa A. Branchek, Charles Gluchowski

Graphical Abstract

A number of 2-amino-2-oxazolines including rilmendine (7) were synthesized in good yield by thermal cyclization of 2-chloroethylurea 2 in the presence of potassium fluoride on alumina. These compounds were assayed for their binding affinity and efficacy at cloned human α adrenergic receptors.
78. You are entitled to access the full text of this document
Studies in Natural Products Chemistry, Vol. 19: Structure and Chemistry, Part E: Atta-ur-Rahman (Ed.); Elsevier Science, Amsterdam, Lausanne, New York, Oxford, Shannon, Singapore, Tokyo, 1997, 850 pages, ISBN 0-444-82815-X, NLG 825.00, US$ 474.00
Phytochemistry, Volume 61, Issue 7, December 2002, Page 880
Jürgen Schmidt Ludger Wessjohann
79. You are entitled to access the full text of this document
Chapter 5.3 Five-membered ring systems: Furans and benzofurans
Progress in Heterocyclic Chemistry, Volume 15, 2003, Pages 167-205
Xue-Long Hou, Zhen Yang, Henry N.C. Wong
80. You are entitled to access the full text of this document
Phytochemical medicinal agents. A quinone-based route to pterocarpins
Tetrahedron Letters, Volume 46, Issue 44, 31 October 2005, Pages 7511-7513
George A. Kraus, Jingqiang Wei

Graphical abstract

The synthesis of 6,9 di-demethoxy kushecarpin A has been achieved by the coupling of a benzofuran anion with a quinone monoketal followed by a regioselective cyclization and a stereoselective hydrogenation reaction.
image

81. You are entitled to access the full text of this document
Synthesis and cytotoxicity of gossypol related compounds
European Journal of Medicinal Chemistry, Volume 35, Issue 9, September 2000, Pages 805-813
Vi-Thuy Dao, Christiane Gaspard, Michel Mayer, Georges H. Werner, Suong N. Nguyen, Robert J. Michelot
82. You are entitled to access the full text of this document
Synthesis of (±)Abyssinone I and related compounds: Their anti-oxidant and cytotoxic activities
European Journal of Medicinal Chemistry, Volume 44, Issue 5, May 2009, Pages 2239-2245
Gudapati Venkateswara Rao, Badrappa Narayana Swamy, Venkateshappa Chandregowda, G. Chandrasekara Reddy

Graphical abstract


image

83. You are entitled to access the full text of this document
Studies on uracils: a facile one-pot synthesis of pyrazolo[3,4-d]pyrimidines
Tetrahedron Letters, Volume 43, Issue 5, 28 January 2002, Pages 895-897
P.J. Bhuyan, H.N. Borah, J.S. Sandhu
The reaction of 6-hydrazino uracils 1 with isocyanates 2 gave access to an efficient one-pot synthesis of pyrazolo[3,4-d]pyrimidines 3 in excellent yields.
image

84. You are entitled to access the full text of this document
Synthesis of analogues of 4-deoxypodophyllotoxin
Tetrahedron, Volume 43, Issue 18, 1987, Pages 4207-4215
Andrrew R. Beard, Michael G. B. Drew, John Mann, Lilan T. F. Wong(née Yeung)
85. You are entitled to access the full text of this document
Synthesis of haginin E, equol, daidzein, and formononetin from resorcinol via an isoflavene intermediate
Tetrahedron Letters, Volume 50, Issue 18, 6 May 2009, Pages 2121-2123
Sie-Rong Li, Po-Yuan Chen, Liang-Yeu Chen, Yi-Fang Lo, Ian-Lih Tsai, Eng-Chi Wang

Graphical abstract


image

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Syntheses of 2,6-anhydro-3-deoxy-5-O-phosphono-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonic acid, its dimeric analogue, and related compounds
Tetrahedron, Volume 53, Issue 47, 24 November 1997, Pages 16041-16060
Masao Shiozaki, Shin-ichi Kurakata, Tohru Tatsuta, Hiroaki Maeda, Masahiro Nishijima

Graphical Abstract

A pyran carboxylic acid analogue of GLA-60 (12a) and its related compounds (12b, 17, 21, and 24) were synthesized in a stereocontrolled manner. Compound 12a showed strong LPS-antagonistic activity.
image

87. You are entitled to access the full text of this document
Solid supported synthesis of structurally diverse dihydropyrido[2,3-d]pyrimidines using microwave irradiation
Tetrahedron Letters, Volume 46, Issue 8, 21 February 2005, Pages 1345-1348
Anu Agarwal, Prem M.S. Chauhan

Graphical abstract

A library of dihydropyrido[2,3-d]pyrimidines has been synthesized on solid support using microwave irradiation.
image

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Syntheses and properties of image-aminopyrimidines
Tetrahedron, Volume 49, Issue 19, 7 May 1993, Pages 3947-3958
Kohfuku Kohda, Isao Kobayashi, Kenji Itano, Shoji Asano, Yutaka Kawazoe

Graphical Abstract

image
-Aminated pyrimidine bases and nucleosides were synthesized and physicochemical properties of the
image
-amino group and its substituent effects on UV absorption and basicity of the pyrimidine nucleus are reported.
image

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An efficient synthesis of lamellarin alkaloids: synthesis of lamellarin G trimethyl ether
Tetrahedron Letters, Volume 42, Issue 6, 5 February 2001, Pages 1205-1208
Somsak Ruchirawat, Thumnoon Mutarapat
Graphic
image

90. You are not entitled to access the full text of this document
Glycosyl Ureides
Advances in Carbohydrate Chemistry, Volume 13, 1958, Pages 215-236
Irving Goodman
91. You are entitled to access the full text of this document
Synthetic immunoadjuvants: application to non-specific host stimulation and potentiation of vaccine immunogenicity
Vaccine, Volume 10, Issue 14, 1992, Pages 1000-1006
Ichiro Azuma
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Tetrahedron reports on organic chemistry
Tetrahedron, Volume 64, Issue 12, 17 March 2008, Pages I-XXI
93. You are entitled to access the full text of this document
Synthesis and thrombolytic properties of some flufenamate derivatives
Thrombosis Research, Volume 12, Issue 4, April 1978, Pages 707-711
M. Sakarellos-Daitsiotis, M. Verlander, R. Doolittle, M. Goodman
94. You are entitled to access the full text of this document
Structural requirements of muscarine, 1,3-dioxolane and their analogues for agonist activity at cholinergic receptors
International Journal of Pharmaceutics, Volume 15, Issue 3, July 1983, Pages 223-234
R. F. Timoney
95. You are entitled to access the full text of this document
Synthesis and biological evaluation of 9-substituted tetracycline derivatives
Bioorganic & Medicinal Chemistry Letters, Volume 12, Issue 16, 19 August 2002, Pages 2163-2165
Darrell J. Koza, Yaw A. Nsiah

Graphical Abstract

The synthesis of a new class of novel tetracycline derivatives via transition metal-based chemistry is reported.
image

96. You are entitled to access the full text of this document
A concise synthesis and in vitro cytotoxicity of new labdane diterpenes
Bioorganic & Medicinal Chemistry Letters, Volume 8, Issue 23, 1 December 1998, Pages 3295-3298
Mankil Jung, Imju Ko, Seokjoon Lee, Sun Ju Choi, Byoung Hee Youn, Soo Kie Kim

Graphical Abstract

Labdane terpenes first synthesized shows in vitro cytotoxicity comparable to that of mitomycin C and adriamycin.
image

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Subject Index
Studies in Natural Products Chemistry, Volume 32, Part 12, 2005, Pages 1209-1252
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Synthesis of nectrisine and related compounds, and their biological evaluation
Tetrahedron, Volume 55, Issue 28, 9 July 1999, Pages 8353-8364
Yong Jip Kim, Akira Takatsuki, Naoto Kogoshi, Takeshi Kitahara

Graphical Abstract

Novel synthesis of potent glucosidase inhibitors, nectrisine and its related derivatives from the corresponding lactams is described. And the results of biological evaluation are also described.
image

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Recent advances in the synthetic applications of the oxazaborolidine-mediated asymmetric reduction
Tetrahedron, Volume 62, Issue 33, 14 August 2006, Pages 7621-7643
Byung Tae Cho

Graphical abstract


image

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CDP840. A prototype of a novel class of orally active anti-Inflammatory phosphodiesterase 4 inhibitors
Bioorganic & Medicinal Chemistry Letters, Volume 12, Issue 11, 3 June 2002, Pages 1451-1456
R. P. Alexander, G. J. Warrellow, M. A. W. Eaton, E. C. Boyd, J. C. Head, J. R. Porter, J. A. Brown, J. T. Reuberson, B. Hutchinson, P. Turner, B. Boyce, D. Barnes, B. Mason, A. Cannell, R. J. Taylor, A. Zomaya, A. Millican, J. Leonard, R. Morphy, M. Wales, et al.

Graphical Abstract

The discovery, synthesis and biological activity of a novel series of triarylethane phosphodiesterase 4 inhibitors is described.
image

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Synthesis of chiral 1,2-diols and related compounds of biological activities via stepwise ring fission of 5-alkyl-6,8-dioxabicyclo[3.2.1]octane skeleton
Tetrahedron Letters, Volume 27, Issue 2, 1986, Pages 231-234
Yukio Masaki, Yuzuru Serizawa, Kinnosuke Nagata, Hirohisa Oda, Hiromu Nagashima, Kenji Kaji
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